Precision-engineered PTFE, PFA and FEP hoses for fluid systems, bearing and cooling systems, and more!
Do you have highly sensitive, ultra-pure, chemically demanding and thermally stressed processes in biopharmaceuticals or pharmaceutical development? We offer tailor-made, certified PTFE, PFA and FEP hoses as safe connection systems.
Biopharmaceuticals & Chemistry – High-performance PTFE and PFA tubing
Fluid systems, storage and cooling systems for the biopharmaceutical industry
Where highly sensitive media need to be safely conveyed, stored, temperature-controlled or metered, the quality of the hose solution is crucial to process stability, product protection and plant reliability. This is precisely where FEP, PTFE and PFA hoses, for example, demonstrate their strengths: in applications where chemical resistance, high purity and robust material performance are essential. For the biopharmaceutical industry, pharmaceutical development or storage and cooling systems, the Masterflex Group offers high-performance hose systems that can be precisely tailored to the handling of sensitive media and complex system requirements. This results in connection solutions that effectively combine safety, flexibility and regulatory compliance in a demanding industrial environment.
High-purity PFA hose solutions made from raw material-certified fluoropolymers offer a chemically inert, low-contamination and process-stable alternative to conventional stainless steel pipe systems and fittings. The Masterflex Group develops ultra-high-purity, high-performance biopharmaceutical PTFE and PFA hoses that are specifically designed to meet the requirements of modern biotech and pharmaceutical facilities.
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PTFE and PFA hoses for the conveyance of substances sensitive to metals
Safe plastic hoses for the conveyance of metal-sensitive substances
When conveying metal-sensitive substances, maximum media compatibility and a particularly inert material base are essential. PTFE and PFA hoses facilitate safe and gentle media handling in these applications, as they can be designed for highly pure and sensitive substances and minimise the risk of undesirable interactions during the process. In the chemical and pharmaceutical industries, certified raw materials such as Teflon™ and COAs are standard practice for us. We are distinguished by our in-depth understanding of biopharmaceutical and biotechnological applications and our close collaboration with OEMs and end-users throughout the entire product life cycle.
Storage and refrigeration systems in the pharmaceutical industry
Fluid transfer for storage and cooling systems in the pharmaceutical industry
In storage and cooling systems within the pharmaceutical industry, liquids and sensitive media often need to be transported reliably under constant temperature conditions. PTFE and PFA hoses for the chemical and pharmaceutical sectors offer a robust solution where chemical resistance, temperature tolerance and long-term process reliability are required in cooling or supply systems. For confined installation spaces or specialised applications, we design and manufacture bespoke solutions for you.
FEP hoses – for the conveyance of chemicals and pharmaceutical-grade fluids
Safe media conveyance with high-performance FEP hoses
FEP hoses from the Masterflex Group are ideal for applications where chemical and pharmaceutical media need to be conveyed safely, transparently and in a controlled manner. They offer advantages in process monitoring, flexible integration into plant systems and in media conveyance systems that require clean, stable handling.
Connection of filter units and ventilation systems
Advantages of PTFE, HP-PFA and FEP hoses over stainless steel pipes
- Unlike stainless steel, the risk of biofilm formation is very low
- No welded seams, resulting in fewer microbiological weak points and extremely low levels of extractables
- No sight glasses required, as translucent hoses allow process media to be seen
- Greater flexibility for plant retrofits and new generations
- No metal ions
- Reduced cleaning and maintenance requirements (CIP)
- Reduced risk of contamination due to homogeneous internal surfaces
- Faster installation and simpler validation
FEP tubing: Example of use – filling of generic medicines
Manufacturers of plastic hoses for the filling of medicines and generic drugs
Every cleanroom and laboratory application places different demands on bend radius, air volume, pressure conditions, temperature behaviour, hygiene and integration with existing systems. When filling medicines or generic drugs, media must be fed precisely and reliably to the filling point under hygienically controlled conditions. FEP-based hose solutions from Masterflex Group subsidiary APT are particularly well-suited to this purpose thanks to their chemical resistance, transparency and ease of integration into sensitive filling systems, as required in pharmaceutical packaging and filling environments.
Connecting tanks, modules and dosing points
Connecting tanks, modules and dosing points – PTFE hoses and more
Wherever tanks, dosing modules, analysis points or transfer stations are connected to one another, hose systems offering high adaptability and reliable fluid handling are required. PTFE and PFA hoses support such applications thanks to their versatility in complex fluid systems within the chemical and pharmaceutical industries. Furthermore, PTFE hoses – that is, extruded hoses without a metal spiral – impress with their extremely low coefficient of friction and high mechanical strength at high temperatures.
Cleanroom hose systems – fluoropolymer solutions for sensitive, high-end applications
With Teflon™ Diamond – high-purity PFA hoses for high-end applications
APT, a valued member of the Masterflex Group, develops bespoke high-purity fluoropolymer solutions. PFA hoses are characterised by their high chemical resistance, purity and temperature stability. They are used in sectors such as the chemical, pharmaceutical, semiconductor and laboratory industries, where reliable materials are crucial. APT offers a wide range of PFA hoses, which are precision-manufactured and optimised for use in demanding processes. APT distinguishes between two categories of PFA tubing: standard PFA tubing offers the highest levels of chemical resistance, purity and temperature stability, and is ideally suited to demanding applications in the chemical, pharmaceutical, semiconductor and laboratory sectors. High-purity PFA tubing is designed for critical processes with the highest purity requirements, complies with the SEMI F57-0301 standard and is used in particular in the semiconductor, photovoltaic, pharmaceutical and biotechnology industries.
Hose systems for temperature-controlled supply in cooling and ancillary processes
Hoses for controlled media transport in the biopharmaceutical industry
In temperature-controlled ancillary processes, cooling circuits or fluid-based supply systems, media must be transported continuously under controlled conditions. PTFE and PFA hoses for the chemical and pharmaceutical industries are suitable for such applications where thermal resilience, chemical resistance and long-term stable performance are required.
Consultancy and development for bespoke hose systems
APT’s fluoropolymer hoses are synonymous with the highest purity, excellent chemical resistance and exceptional temperature stability. Thanks to state-of-the-art extrusion technology, APT manufactures hoses from high-quality materials such as PTFE, PFA, FEP, ETFE, ECTFE, PVDF and THV – precisely tailored to the requirements of a wide range of industries. In biopharmaceutical and pharmaceutical applications, hose systems must not only be technically capable but also designed to meet regulatory requirements. PTFE and PFA hoses should therefore be assessed in terms of purity, chemical suitability, temperature resistance, documentation and application-specific compliance.
It is crucial that the hose system (which can also be customised) can be reliably integrated into sensitive processes and supports both product quality and process reliability in the long term. Particularly in chemical and pharmaceutical environments, a material- and application-specific design is therefore a key factor for success.
The requirements for hose systems in biopharmaceuticals, fluid systems, and storage and cooling systems are high and often highly specific. That is why the Masterflex Group supports its customers every step of the way, from requirements analysis through material selection to the development of bespoke system solutions. This results in safe hose solutions for the chemical and pharmaceutical industries that not only impress in terms of chemical and thermal performance, but also function reliably in complex plant environments and can be seamlessly integrated into existing processes.
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Hoses are better than stainless steel pipework for the food, pharmaceutical and biotech sectors
Before a product such as a vaccine, a tablet, a dairy product or a microchip is completed, it usually goes through numerous process steps in complex industrial plants. The journey takes the product through kilometres of hose lines and piping systems with numerous connection points – from tank farms, through reactors and fermenters, to downstream processing. Pumps move the fluid flows, valves control them precisely, whilst sensitive sensors monitor the processes. In unit operations and process equipment, the media are further processed until the end product is finally ready for sterile filling or controlled dispensing. For pure performance, we support our customers as a reliable supplier and development partner throughout the entire value chain.
Hoses for the food and pharmaceutical industries – your point of contact
Food-grade FDA-approved plastic tubing
Do you manufacture products yourself or build plant for the food industry? Masterflex Group develops FDA-compliant hose and connection solutions for demanding processes in the food and pharmaceutical industries. Whether in food production and processing, in filling systems or in pharmaceutical production environments: our food-grade hoses stand for quality, safety and technical performance. Find out more
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Airflow and supply applications
In the pharmaceutical sector, plastic hoses are used in cleanroom technology, for controlled airflow in filling plants, isolators, sterile areas, and extraction and ventilation systems. They protect production processes from particles and contamination, or supply fresh air to the plant, laboratories and staff.
Tablet, powder and capsule production
Pharmaceutical products such as capsules or tablets must be handled and transported with particular care. When active ingredients are used in pharmaceutical production to create precisely dosed tablets, capsules or liquid medicines, every step in the process must be carried out accurately, hygienically and with absolute reliability.
Frequently Asked Questions about Masterflex Group PTFE, FEP and PFA hose solutions
Is it possible to mark or laser-engrave PTFE and PFA hoses?
Yes, we do offer laser-marked fluoropolymer hoses with continuous marking. Whilst hoses made from engineering plastics such as PE or PA are usually marked, this is often not done when fluoropolymers are used, as conventional printing processes simply do not adhere to fluoropolymers. A new laser marking technology now enables marking of impressively high quality. In terms of the printed image, not only text but also logos or safety markings can be printed with razor-sharp clarity.
What are the manufacturing processes used for your fluoropolymer hoses?
APT utilises state-of-the-art production facilities to carry out conventional extrusion, co-extrusion and paste extrusion of PTFE, enabling it to manufacture high-precision, application-specific tubing solutions with the highest levels of dimensional accuracy and functionality.
What are PTFE, FEP and PFA hoses?
PTFE, FEP and PFA hoses are high-performance plastic hoses made from fluoropolymers, which are characterised by high chemical resistance, temperature resistance and excellent purity, making them ideal for demanding media and process applications. Our specialist within the Masterflex Group is APT, based in Düsseldorf.
For which applications are PTFE or PFA hoses suitable in the pharmaceutical industry?
PTFE and PFA hoses are particularly suitable in the pharmaceutical industry for high-purity, chemically aggressive and temperature-sensitive media in applications such as fluid transfer, filling, bioprocessing, CIP/SIP cleaning, analytical and sterile production environments, as well as in single-use systems and pump, valve and dosing lines, or in the high-purity semiconductor front-end.
What are the advantages of PFA tubing?
PFA tubing offers, above all, very high chemical resistance, high purity, temperature stability and a long service life, making it ideally suited to demanding processes in the chemical, pharmaceutical, semiconductor and laboratory sectors. APT distinguishes between standard PFA tubing, designed to meet the highest demands for reliability and durability, and high-purity PFA tubing with a particularly low concentration of extractable substances in accordance with SEMI F57-0301, for highly critical applications in the semiconductor, photovoltaic, pharmaceutical and biotechnology industries.
When are FEP hoses the right solution?
FEP tubing is ideal for conveying media used in the chemical and pharmaceutical industries, where transparency, controlled media flow and ease of integration into plant systems are required. It is frequently used in applications where process visibility and clean handling are important.
What is the minimum diameter for APT FEP hoses?
APT manufactures FEP tubing with internal diameters ranging from a minimum of 0.10 mm to a maximum external diameter of 100 mm. In addition to a wide range of standard dimensions, which we keep in stock, we can produce almost any customised dimensions; on request, these can also be coloured in accordance with the RAL colour chart.
When is a PTFE hose recommended?
A PTFE hose is particularly recommended for applications involving high chemical and thermal stress. For example, in a production laboratory. Where media are corrosive or processes operate under demanding temperature conditions, PTFE provides a particularly robust material base.
Is it possible to get custom-made PTFE hoses?
APT manufactures PTFE hoses with internal diameters ranging from a minimum of 0.30 mm to a maximum external diameter of 20 mm. In addition to a wide range of standard dimensions, which we hold in stock, we can produce almost any customised dimensions; on request, these can also be coloured in accordance with the RAL colour chart.
Are there also bespoke solutions available?
Yes, bespoke solutions can be developed to meet individual system requirements. This includes, for example, special connection solutions, customised geometries, specific material combinations or complex fluid systems for research, development and production.
What is the most important factor when it comes to hoses for fluid systems?
It always depends on the specific requirements. As a general rule, the most important factors for hoses used in fluid systems are resistance to the fluids, purity, pressure and temperature resistance, and consistently reliable and safe process performance.
Why are PTFE and PFA hoses suitable for substances that react with metals?
Because they can be designed for inert and media-compatible applications, thereby reducing the risk of interactions with sensitive substances. This makes them particularly suitable for sensitive chemical and pharmaceutical processes.
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